Selecting the right DC-DC converter is a critical decision in modern power system design, with implications for efficiency, reliability, cost, and overall system performance. Engineers must consider whether an isolated or non-isolated topology is best suited for their application, taking into account factors such as safety requirements, noise immunity, signal integrity, size, weight, and power density. 

Isolated converters provide essential protection in high-voltage or safety-critical applications and can help eliminate ground loops and generate negative voltage rails, while non-isolated converters offer higher efficiency, smaller size, reduced weight, and lower cost, making them ideal for battery-powered and high-performance systems. Making the right choice often involves a careful analysis of system architecture, functional needs, and regulatory standards.

In a recent article on their Power Supply Blog, TDK-Lambda explores DC-DC converter selection: the differences between isolated and non-isolated designs, where each is most effective, and key engineering considerations for choosing the right topology. Read the article: “When to use Isolated and non-isolated DC-DC Converters“.